Health Benefits of Alpha-Ketoglutarate (AKG)

Health Benefits of Alpha-Ketoglutarate (AKG)

Although our bodies have been producing it naturally since the beginning of humankind, we are now finding out how beneficial AKG can be when taken as a supplement. In combination with a healthy lifestyle, AKG has been suggested to promote the vitality and overall health of humans and small animals. For that reason, among many others, Alpha-Ketoglutarate (AKG) has been growing in popularity as a supplement among people with a wide range of different health goals. Through this pose, you will be able to discover the numerous health benefits associated with AKG as well as how to tell if it is the right supplement to support your lifestyle.

What is Alpha-Ketoglutarate (AKG)?

Organically formed through the energy-producing process that takes place naturally throughout your body’s cells, Alpha-Ketoglutarate (AKG) is a nitrogen-free part of the amino acid chains that are known as glutamine and glutamic acids. When taken as a supplement, this powerful acid has been linked to a number of health benefits that directly impact the skin, bones, and metabolic health.

When it occurs naturally, AKG is especially helpful in healing muscles tissues, injuries, and other wounds. It is commonly used by weightlifters who are more and more frequently opting for supplements that contain AKG due to its ability to increase strength and muscle mass. However, studies suggest that the benefits of the supplement can reach even further than just promoting muscle growth.

AKG has incredible healing and protective qualities within our bodies. In fact, throughout the medical world, doctors are frequently using AKG to aid in the treatment of conditions such as osteoporosis and kidney diseases. It is also administered to patients before and after surgery because of its amazing abilities to heal tissues and protect against any unnecessary damage.

Anti-Inflammatory Properties of Alpha-Ketoglutarate (AKG)

Alpha-Ketoglutarate (AKG) enhances the body’s ability to flush out harmful toxins and waste products. It also prevents these toxins from being absorbed into your body. One of the deleterious waste products that AKG helps to flush out of your body is ammonia, which is a byproduct of protein breakdown. High levels of ammonia are most frequently caused by liver disease, kidney failure, or other genetic disorders. Too much ammonia in the bloodstream can lead to serious physical ailments including brain damage, coma, or even death. Since ammonia is especially high in patients who are undergoing kidney dialysis treatments, it is common for doctors to administer AKG intravenously to their patients. Doctors sometimes also recommend AKG supplements to their patients who are suffering from kidney disease or liver failure.

Since it is a key metabolite that can regulate the way that your cells communicate with each other, AKG can also exert a number of anti-inflammatory effects. Anti-inflammatories are typically used when your body is fighting off an infection or healing itself from injury. They are known to relieve pain, reduce inflammation, and bring down high fevers. In other words, AKG can help the muscles and tissues heal themselves without causing additional pain or discomfort.

How Alpha-Ketoglutarate (AKG) Promotes Metabolic Health

Since it protects against imbalances of deleterious waste products such as ammonia and nitrogen, AKG can help to regulate the immune system, promoting metabolic health. In addition to its anti-inflammatory properties, after you have been taking the supplement regularly for a few weeks, Alpha-Ketoglutarate (AKG) will begin to improve your metabolism. This occurs because it positively impacts your body’s ability to switch between carbohydrate and amino acid energy production. In other words, taking a daily AKG supplement can help the cells that make up your metabolism determine where it is getting their energy from.

Since it is part of the amino acid chain, the presence of AKG throughout your body can improve the production of important proteins such as collagen. Collagen is a protein that is essential in protecting tissues and cells throughout the body. It is especially abundant in the skin, bones, muscles, and tendons. Because of AKG’s unique abilities to help to promote collagen production and reduce fibrosis, it can directly impact the health and functionality of your skin, bones, and gut.

Doctors commonly recommend AKG to patients who suffer from osteoporosis because of its ability to not only strengthen bones but also help them heal themselves. It can also be beneficial in improving the appearance and elasticity of the skin. However, one of the most amazing benefits of AKG is its ability to heal the tissues present within your gut, promoting metabolic health.

Alpha-Ketoglutarate (AKG) and Athletic Performance

Because of its incredible abilities to stimulate protein synthesis while inhibiting protein degradation in muscle tissues, many athletes have made the decision to supplement their fitness regimen with Alpha-Ketoglutarate (AKG) supplements. Amazingly, AKG can also improve your body’s ability to make nitric oxide. Nitric oxide is an important component of making muscle gains because it causes the blood vessels to widen and can stimulate the release of hormones. For these reasons, using AKG supplements is increasingly common for athletes who are focusing on increasing their strength through lifting weights in addition to working on gaining muscle mass.

Although there has not been much research or clinical studies done to support this claim, many athletes and weightlifters have said that supplementing their workouts with AKG helped to improve the results of their weight training. AKG is effective in promoting the development of muscle mass because the natural process that releases it throughout your body is a vital part of cell growth. It is also frequently administered by doctors intravenously to surgery patients in order to help them maintain the composition and resilience of muscles throughout the body, including the heart.

Alpha-Ketoglutarate (AKG)’s Anti-Aging Properties

There have been multiple studies conducted on the astounding benefits that AKG has when it comes to protecting against the symptoms of aging. As your age increases, the levels of Alpha-Ketoglutarate (AKG) that your body’s cells naturally produce will slowly begin to decline. For that reason, it can be especially beneficial to increase your body’s levels of AKG with a supplement that contains it.

Plenty of research studies have suggested that AKG supplements can drastically improve the health of older organisms. This is because of AKG’s incredible ability to positively impact a cell’s capacity to heal itself when it becomes damaged in addition to protecting that cell against damage in the first place. AKG has also been shown to improve the health and well-being of the mitochondria, which is the powerhouse of the cell.

Aging can sometimes lead to epigenome dysregulation, which prevents it from regulating which genes are active or not. However, AKG can promote the well-being and longevity of the epigenome and regulate the activity of your genes. It does this by working in harmony with Vitamin C that you consume through your diet or through supplements.

Although official tests have not yet been conducted on humans, Alpha-Ketoglutarate (AKG) has been proven to extend the lifespan of various small animals and organisms. Not only that, but AKG has also shown promising signs of increasing the health of small animals significantly. So far, tests regarding the anti-aging properties of AKG have been primarily conducted on mice, but the results have been incredibly promising.


Alpha-Ketoglutarate (AKG) is a molecule that makes up proteins and fatty acid chains throughout our bodies. It occurs naturally throughout almost every living cell and when it is produced, it enhances that cell’s ability to heal itself and protect against further damage.  As you can see from this article, there are numerous health benefits to AKG supplements.

When taken in combination with a healthy lifestyle, AKG supplements have been suggested to display anti-inflammatory properties that help your body heal itself and fight off infections. AKG can also promote metabolic wellness through its incredible ability to heal tissues and organs throughout the body. Many athletes supplement their muscle growth by adding AKG into their post-workout routines since it has been shown to help muscle tissue heal in addition to retaining the existing muscles. Perhaps one of the most impressive aspects of AKG is its ability to reduce symptoms of aging in older individuals.